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Πλοήγηση ανά Συγγραφέα "Kossida, S."

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    • A Comprehensive Phylogenetic Analysis of Deadenylases 

      Pavlopoulou, A.; Vlachakis, D.; Balatsos, N. A. A.; Kossida, S. (2013)
      Deadenylases catalyze the shortening of the poly(A) tail at the messenger ribonucleic acid (mRNA) 3'-end in eukaryotes. Therefore, these enzymes influence mRNA decay, and constitute a major emerging group of promising ...

    • An Integrated In Silico Approach to Design Specific Inhibitors Targeting Human Poly(A)-Specific Ribonuclease 

      Vlachakis, D.; Pavlopoulou, A.; Tsiliki, G.; Komiotis, D.; Stathopoulos, C.; Balatsos, N. A. A.; Kossida, S. (2012)
      Poly(A)-specific ribonuclease (PARN) is an exoribonuclease/deadenylase that degrades 3'-end poly(A) tails in almost all eukaryotic organisms. Much of the biochemical and structural information on PARN comes from the human ...

    • A novel mutation of the hGR gene causing Chrousos syndrome 

      Nicolaides, N. C.; Geer, E. B.; Vlachakis, D.; Roberts, M. L.; Psarra, A. M. G.; Moutsatsou, P.; Sertedaki, A.; Kossida, S.; Charmandari, E. (2015)
      Background Natural mutations in the human glucocorticoid receptor (hGR, NR3C1) gene cause Chrousos syndrome, a rare condition characterized by generalized, partial, target-tissue insensitivity to glucocorticoids. Objective ...

    • Using graph theory to analyze biological networks 

      Pavlopoulos, G. A.; Secrier, M.; Moschopoulos, C. N.; Soldatos, T. G.; Kossida, S.; Aerts, J.; Schneider, R.; Bagos, P. G. (2011)
      Understanding complex systems often requires a bottom-up analysis towards a systems biology approach. The need to investigate a system, not only as individual components but as a whole, emerges. This can be done by examining ...

    • Which clustering algorithm is better for predicting protein complexes? 

      Moschopoulos, C. N.; Pavlopoulos, G. A.; Iacucci, E.; Aerts, J.; Likothanassis, S.; Schneider, R.; Kossida, S. (2011)
      Background: Protein-Protein interactions (PPI) play a key role in determining the outcome of most cellular processes. The correct identification and characterization of protein interactions and the networks, which they ...